I use VPN on all my personal devices and 100% block all of Google but my work computer is either company VPN or straight “normal” Internet.

From time to time I have to check out YouTube from the work computer and since they’ve got no data on my home IP address, it’s wild seeing the content of the ads shift from irrelevant (non-targeted) from my home IP to highly targeted on the work VPN (it’s clear they target the demographics of my company).