Looking at the 2023 cases by month, the researchers noted that the surge in situs inversus began in April and continued to June before returning to background rates in July.

The authors acknowledge that “no conclusions” can be drawn from the current report as to the cause of the unusual spike. However, they call for further research to understand what was behind the uptick and the possible role of SARS-CoV-2. The good news is that most people with situs inversus have normal life spans.