I’ve heard rumblings about the beta amyloid hypothesis being weak or incomplete for a while. Does anyone better versed in the research know what alternative hypotheses have shown promise?
The amyoid hypothesis has always been weak. It should have ended in 2008 when random brain imaging in elderly showed healthy brains full of amyloid. But then fake manuscripts appeared to keep the mafia fed, even in other neurodegenerative diseases, this even took down the President of Stanford. This was only really promoted by US science and Pharma, and no one who offered alternatives was funded.
Elderly who maintain all their vaccinations, especially for herpes zoster (shingles), have significantly less dementia. it’s down to how many infections the eldery brain has to endure, because these infections cause a dangerous immune reponse that stresses out neurons that already have weak mitochondria due to ageing. AD is also better tied to metabolic syndromes and high levels of DNA damage. People with Down’s Syndrome have a huge incidence of alzheimer because of proteins made on chromosome 21. But all that research and any future research was killed in 2025.
It really makes one question the real motivation of RFK jr.
But the biggest problem in AD research is that many different diseases have a common outcome. There are many versions of dementia with very different causes, much like the hundreds of types of cancer. But clearly, the attitude of “it’s just the flu” has to change.
I’ve heard rumblings about the beta amyloid hypothesis being weak or incomplete for a while. Does anyone better versed in the research know what alternative hypotheses have shown promise?
The amyoid hypothesis has always been weak. It should have ended in 2008 when random brain imaging in elderly showed healthy brains full of amyloid. But then fake manuscripts appeared to keep the mafia fed, even in other neurodegenerative diseases, this even took down the President of Stanford. This was only really promoted by US science and Pharma, and no one who offered alternatives was funded.
Elderly who maintain all their vaccinations, especially for herpes zoster (shingles), have significantly less dementia. it’s down to how many infections the eldery brain has to endure, because these infections cause a dangerous immune reponse that stresses out neurons that already have weak mitochondria due to ageing. AD is also better tied to metabolic syndromes and high levels of DNA damage. People with Down’s Syndrome have a huge incidence of alzheimer because of proteins made on chromosome 21. But all that research and any future research was killed in 2025.
It really makes one question the real motivation of RFK jr.
But the biggest problem in AD research is that many different diseases have a common outcome. There are many versions of dementia with very different causes, much like the hundreds of types of cancer. But clearly, the attitude of “it’s just the flu” has to change.
More vaccinations = less dementia.