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Cake day: June 30th, 2023

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  • Many families have recessive fucked alleles that cause all kinds of problems. An allele is a variant of a gene. You need two copies of a recessive allele for that gene to be expressed (do something).

    Every fucked allele the parents share has a 25% chance of being expressed in the child. The more DNA the parents share the more fucked alleles they share. Usually… sometimes the opposite happens and the number of bad alleles is reduced in the child. Inbreeding can lead to fucked animals and “perfect” ones. Weird stuff.

    Now you might be thinking “why do families have so many fucked alleles?”

    That’s a good question. The thing about carrying a single recessive, fucked allele is that it doesn’t do anything to you. Mutations happen all the time and so these alleles are floating around and multiplying constantly.

    It’s only a problem on the odd chance that they get expressed which is most often when family members produce offspring.

    So it’s worth noting that this is the type of thing that we can check for these days. In some cultures it’s acceptable to marry a cousin and I’ve heard that they check for any genetic issues before proceeding when they live in a first world country.











  • sosodev@lemmy.worldtointernet funeral@lemmy.worldMatchbook
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    11 months ago

    I remember talking to an older fella about his experience becoming a programmer back in the 60s (I think). He told me that he decided it was time to start a career so he went to a nearby IBM office and asked for a job. They gave him an aptitude test and then hired him the same day. He wrote code for their mainframes until he retired.



  • This has been said in the thread already but I want to try and boil it down a bit. Your question is about intuition vs evidence. Science used to involve a lot more intuition. Many things that the public believed to be true were just educated guesses with little evidence to back them up.

    Over time we realized through research that a large number of these reasonable guesses were completely wrong. So now intuition in science has been largely limited to the hypothesis and the hypothesis is mostly worthless without evidence.

    We’ve also seen in the modern day just how fucked up human intuition can be. We largely have intuition to thank for: flat earth, anti vax, snake oil, etc.