Biggest issue I see is that these LLMs tend to repeat themselves after a surprisingly short number of times (unless they’re sufficiently bloated like ChatGPT).
If you ask any of the users of Sillytavern or RisuAI they’ll tell you that these things have a long tail of not being very creative.
The key is to get one where you can widen the spray and squeegee everything off.
Yea I should have put an asterisk.
I’d go further and say you should ask a pharmacist about questions like these. Even better is to ask a compounding pharmacist, as a doctor or retail pharmacist might just recite the pharmacopeia to you while a compounding pharmacist will probably explain in more detail (likely as a play to offer their services lol).
So it technically depends on the extended release formulation, so from a layman’s perspective, yes you should likely ask your doctor or even better ask a compounding pharmacist (as a general rule if you have questions about medication you’re better off asking a pharmacist rather than a doctor.)
Given that…
From a technical perspective the only definition of extended release is a lag phase after ingestion. This means there’s no immediately discernable difference between delayed release through anti-dissolution coating and slow dissolution through a hard-to-dissolve substance. (Even when you read something like two different pills saying delayed release vs extended release, there’s no legal difference and the FDA doesn’t give a fuck about the naming. This might be different in other countries so Americans benefit from other Country’s health systems in naming. I’m not sure.)
Coating-type pill formulations should not be crushed.
Suspension-type formulations actually can be crushed to a certain degree. Typically humans aren’t going at the pills like crazy in a mortar and pestle and don’t have the strength to separate the suspension properly so it’ll still have a slowed release effect. But yea if you smash them too hard then yea you can actually mess up the way that works.
By the way if anyone’s curious yes you can crush up Viagra, put it in Vaseline, and use it as a cream.
Yes you can put it there, and yes it’s effective.
I’ve done it multiple times for people that would regularly go over that five hour limit, because skin absorption is slower and weaker than intestinal absorption.
Only EC(Enteric Coated) pills and capsule interiors cause they protect the pill against stomach acid until it reaches the intestine.
If it’s got a shiny exterior like an Advil it’s Enteric coated. If it’s a capsule with EC granules you’re gonna have a hard time crushing it anyway.
You’re probably not going to have a problem with those though because Enteric coating is super sweet and capsules are usually neutral in flavor, so there’s not much reason to try and hide the bitterness. For everything else there’s no real functional difference between a smashed pill and a whole pill in your stomach.
Edit: You should definitely consult with a pharmacist or even better a compounding pharmacist about this if you’re not sure what kind of pill you’re looking at, though.
Former pharmacy tech here, 8 years compounding pharmacy.
Get a mortar and pestle, crush it up and put it in whatever.
If not then use yogurt or something gooey.
“rent control” and “managed gentrification” are kind of two sides for same coin
The basic tenet is that downward pressure on any existing investment tends to put upward pressure on new investments from similar firms, sometimes pricing investors out.
In this case it’s rent control putting caps on return outside market fluctuations. It causes builder firms to take on the financial burden of getting return on investment by pricing newer units higher. This prices out people and sometimes locks them into the rent control system as they can’t afford the now higher priced newer housing.
This causes fewer units to be built as now you have to target a smaller but more financially viable market segment so “affordable housing” takes a slump.
The asterisk here is that people living in their current housing don’t end up on the street, but it severely hampers city growth, as new tenents can’t find affordable housing.
By Itself I don’t think rent control is a net positive thing for a community, but rent control to keep tenents in their existing homes combined with heavy investment into real estate development from the government is a great one-two punch to eliminate homelessness.
Problem is #2 costs money while #1 doesn’t so… Most of the time you only see politicians trying to focus down on the rent control.
So, this ain’t a HARD LINE finding, but it’s a popular opinion in economist circles.
Here’s a great video on the topic by unlearning economics:
How do you do this with a tablet? Can you buy like a wheel sensor or something?
Not to rain on your parade but:
https://phys.org/news/2024-08-scientists-oceans-mars-deep.html
Using seismic activity to probe the interior of Mars, geophysicists have found evidence for a large underground reservoir of liquid water—enough to fill oceans on the planet’s surface.
It’s located in tiny cracks and pores in rock in the middle of the Martian crust, between 11.5 and 20 kilometers below the surface. Even on Earth, drilling a hole a kilometer deep is a challenge.
Ain’t nobody getting to that water anytime soon.
Saving this comment for posterior
In regards to the open source models, while it makes sense that if a developer takes the model and does a significant portion of the fine tuning, they should be liable for the result of that…
This kind of goes against the model that open source has operated on for a long time, as providing source doesn’t represent liability. So providing a fine-tuned model shouldn’t either.
My one dark hope is AI will be enough of an impetus for somebody to update DMCA
> pay once, get access to everything everywhere
> thinks about Elsevier
OH GOD PLEASE NO
I seriously doubt the viability of this, but I’m looking forward to being proven wrong.
They should probably do the same with cascade, seeing as that license seems to be more restrictive as well
Judging by my bank account I’m transitioning to non-profit status as well.
I think Steam does have enough influence to be able to pull a sizable chunk of users away from windows.