• AnarchistArtificer@slrpnk.net
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    2 months ago

    In a genetic sense, it is a dysfunction of the gene that causes this. It’s neat because we can actually trace the history of human migrations by looking at the distribution of this particular allele (version of a gene). We have analysed DNA from ancient remains of early Europeans and found that the A allele is absent. It appears like this version of the gene first emerged in an ancient East Asian population.

    This gene also determines whether you have dry or sticky ear wax. It’s a neat gene because it’s uncommon for physical human traits to be controlled by one gene — most human characteristics are controlled by multiple genes (polygenic traits); ginger hair is another example of a monogenic trait. ABCC11 is neat because it affects multiple traits: sweat smell and earwax dryness.

    It might also be implicated in breast cancer risk (I can’t tell whether that’s in an increased risk or decreased risk), but we don’t really understand yet how that would work. From skimming the research, I would say we generally don’t understand how this gene works at all. We do know some stuff about it and how/why it works, but we’re still a decent way off of actually understanding its implications.

      • 1995ToyotaCorolla@lemmy.world
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        2 months ago

        I don’t have an answer for you, but I love how seemingly random it is. Like someone reached into a raffle bowl and was like “Okay ABCC11 you get… Earwax and <shuffles around> …ah. Body odor”.

      • flying_sheep@lemmy.ml
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        2 months ago

        Did you know that you can click the headline to get to an actual article that you can read, which answers this question?

        • isolatedscotch@discuss.tchncs.de
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          2 months ago

          guilty! should have read it before commenting blindly

          for everyone else reading,

          a dysfunctional ABCC11 gene is also connected to drier, less goopy earwax. “So less of that means less body odor, and also translates to dry earwax.”

      • CookieOfFortune@lemmy.world
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        2 months ago

        Maybe affects the kind of bacteria that can grow on your body? That’s where the smell in your armpits come from and earwax stops bacteria.