2050s for 1st edition, I think current edition is 2070s. Dragons started waking up in the early 2010s though. There has also been significant geopolitical upheaval, especially in the Americas and Europe. The general assumption is that a nuyen being about 1 modern dollar is about the right ballpark.
Labour conditions shouldn’t need regulation, we should just recognise another being’s suffering.
Though if we are going to have governments, they might as well do something useful.